home
***
CD-ROM
|
disk
|
FTP
|
other
***
search
/
Shareware Overload Trio 2
/
Shareware Overload Trio Volume 2 (Chestnut CD-ROM).ISO
/
dir26
/
med9409d.zip
/
M9490684.TXT
< prev
next >
Wrap
Text File
|
1994-09-24
|
3KB
|
41 lines
Document 0684
DOCN M9490684
TI [Initial clinicopathological manifestations of malignant
lymphoproliferative processes in patients with human immunodeficiency
virus seropositivity. Study of 40 cases]
DT 9411
AU Bellmunt J; Ribas A; Ocana I; Capdevila JA; Ruiz-Marcellan MC; Giralt J;
Sole LA; Seccion de Oncologia Medica, Unidad de Enfermedades;
Infecciosas, Hospital General Vall d'Hebron, Barcelona.
SO An Med Interna. 1994 May;11(5):217-23. Unique Identifier : AIDSLINE
MED/94339274
AB We analyzed the series of 40 malignant lymphoproliferative diseases
(MLD) in HIV positive patients, diagnosed between 1986 and 1993 in a
University Hospital in Spain. Median age was 32 years. 52% of the
patients belonged to the intravenous drug users risk group, and 30% were
homosexual. 26 patients were diagnosed of a non-Hodgkin's lymphoma
(NHL), 8 of Hodgkin's disease (HD) and 6 of a primary central nervous
system lymphoma (PCL). The 6 patients with a PCL (median CD4 of 20
cells/mm3, 80% antecedent AIDS criteria) and 13 NHL with histology of
immunoblastic, large cell, plasmablastic, and high grade lymphoma
non-otherwise specified (median CD4 of 291, 58% with AIDS criteria)
tended to appear in patients with a deteriorated clinical and
immunological status due to the underlying HIV infection. However, the
14 small non-cleaved cell NHLs appeared in patients without a previous
AIDS-defining condition (93% of the cases, p = 0.065 compared with other
NHL histologies). Finally, 8 patients with HD had a low CD4 cell count
(median 103 cells/mm3, p = 0.049 compared with median CD4 in NHL
patients) without other previous AIDS criteria. In conclusion, The
presenting characteristics of HIV positive patients with MLD allows to
define four subgroups of patients with a high clinicopathological
correlation.
DE Adolescence Adult Central Nervous System Neoplasms/PHYSIOPATHOLOGY
English Abstract Female Hodgkin's Disease/PHYSIOPATHOLOGY Human HIV
Seropositivity/*PHYSIOPATHOLOGY Lymphoma/PHYSIOPATHOLOGY Lymphoma,
AIDS-Related/*PHYSIOPATHOLOGY Lymphoma, Non-Hodgkin's/PHYSIOPATHOLOGY
Male Middle Age JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).